Abstract Search

ea0041gp237 | Thyroid Cancer (1) | ECE2016

The origin of patients with inherited medullary thyroid cancer, who are carriers of the rare exon 8 mutation (G533C) of the RET gene in Greece

Saltiki Katerina , Anagnostou Elli , Angelopoulou Anastasia , Kouki Sofia , Apostolakis Michail , Sarika Lida , Papathoma Alexandra , Alevizaki Maria

Introduction: Mutations in the ret gene are responsible for the transmission of inherited medullary thyroid cancer (MTC). In recent years a high prevalence of the rare exon 8 mutation (G533C) has been found in patients with inherited MTC in Greece. The aim of this study was to record with more detail the place of origin of these families in the country.Design: We analysed the details of 44 patients belonging to 22 families who were c...

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ePoster

ea0037gp.23.08 | Thyroid – diagnosis | ECE2015

Clinical characteristics in sporadic and familial medullary thyroid carcinomas: worse outcome in sporadic cases even when disease stage at diagnosis is similar

Saltiki Katerina , Spanou Loukia , Kouki Sofia , Rentziou Gianna , Vasileiou Vasiliki , Anastasiou Eleni , Alevizaki Maria

Objectives: Medullary thyroid carcinoma (MTC) has varying clinical course with familial cases (fMTC) diagnosed earlier than sporadic ones (sMTC). We examined the presentation of these entities in our centre.Methods: 223 MTC patients (familial: 42.6%, males: 36.8%) were followed for 0.930 years (mean 6.23±5.9, median 4.0 years). 44 (19.7%) fMTC patients were operated after genetic screening.Results: Median age at diagnosi...

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Endocrine Abstracts

The origin of patients with inherited medullary thyroid cancer, who are carriers of the rare exon 8 mutation (G533C) of the RET gene in Greece

Clinical characteristics in sporadic and familial medullary thyroid carcinomas: worse outcome in sporadic cases even when disease stage at diagnosis is similar

BiosciAbstracts